Sylvester Croom began his coaching career in the SEC as an assistant at the University of Alabama for 11 seasons, during his time there, Croom participated in 10 bowl games, 2 national championships and coached 4 eventual NFL first-round draft picks. In 2004 he became the first African American head coach in SEC history when he took over as coach of the Mississippi State football program. Croom coached the Bulldogs for five seasons. Croom was named SEC Coach of the Year at the end of the 2007 season.
Croom additionally spent time with a number of NFL teams as the Runnings Backs Coach including Tampa Bay Buccaneers, Indianapolis Colts, San Diego Chargers, Green Bay Packers, St. Louis Rams, Jacksonville Jaguars, and the Tennessee Titans. He also worked as the Offensive Coordinator for the Detroit Lions from 1997- 2003.
In 2007, Croom attended a gathering hosted by President George W. Bush in observance of Black History Month. His late father, Sylvester Croom Sr. has been recognized by the University of Alabama, where he served as the team chaplain, as one of the 40 pioneers of civil rights in the state.